William Pu, MD, is the Director of Basic and Translational Cardiovascular Research in the Department of Cardiology at Boston Children’s Hospital, and the Aldo R. Castañeda Professor of Pediatrics at Harvard Medical School. Dr. Pu has broad expertise in cardiac biology that includes cardiac development, heart failure, cardiac regeneration and in vitro cardiac disease modeling. His lab has made fundamental discoveries in gene regulation in developing and diseased hearts, particularly in the area of transcriptional regulation. His lab is currently studying the pathogenesis of inherited heart diseases and using insights gained to developed targeted therapies.

Dr. Pu completed his combined BS-MS degree at Yale University and obtained his MD degree from the Harvard Medical School/MIT Science and Technology Program in 1993. He trained in Pediatrics and Pediatric Cardiology at Boston Children's Hospital. He received his training in basic research in the laboratories of Kevin Struhl, David Clapham, and Seigo Izumo. He established an independent research lab at Boston Children’s in 2004.